In Vitro Fertilization 

Problems Possible to Experience During Treatment

 2018-06-22

A) NO REPONSE TO THE TREATMENT

5% of the patients do not response to the treatment despite the suitable treatment and no egg is produced. The treatment can be tried again by using medicines increasing the egg count and quality (testosteronereinforcement, antioxidants, growth hormone).

 

B) INFECTION AND BLEEDING

These are rare situations. Necessary measurements are taken by usage of antibiotics during the treatment, disuse of aspirin and examination of blood parameters before the treatment.

C)  HYPERAROUSALSYNDROME (OHSS-Ovarian hyperstimulation syndrome)

This is a serious complication generally experienced in patients who has developed abundant of egg (polycystic over) and have young and weak body structure. The main reason is fluid and electrolyte imbalance based on excessive increase in estrogen and it is understood that this complication is always developed right after cracking treatments containing HCG. Depending on the treatment, problems such as the fluids leaking into the cavities outside of the veins and hyper-viscosity occur. Measurements such as use of contraceptive pills in the beginning, medicines such as low dose aspirin, metformin and use of low dose egg-stimulant medicines are taken for the disease not to be developed.Close follow-up during the treatment process, following the estradiol level in the blood if necessary and drug-free period is followed if it is high (above 4000 pg/ml), avoiding hcg or low dose hcg, CRACKING BY ANALOG, reducing the fluid leakage with medicines containing cabergoline are carried out.If the risk continues despite all these, it might be necessary to gather all the eggs and freezing the embryos. The period of first 1 week is always very important for these patients. It is suggested to take abundant water and other liquid foods. Even though the transfer is not carried out, the follow-up of vital functions (urination, blood parameters, weight follow-up) continue and the risk ends when the patient has her menstruation.

The risk is dropped to a level close to zero by preferring to crack the eggs by analog and freezing all of the embryos and transferring them later in our center.

 D) MULTIPLE PREGNANCY

The multiple pregnancy rate increases as much as the pregnancy rate with the transfer of 2 or more embryos. This rate is 25- 30% in the transfer of 2 embryos.It is experienced more to have early pregnancy losses, premature births and other mother and baby complications in multiple pregnancies.Complications belonging to the pregnancy (undesired result) increase by 8 times in twin pregnancies and 30 times in triplet pregnancies. Therefore, the risk for multiple pregnancy is reduced by transferring embryo in the amount determined by laws.

 E)  ECTOPIC PREGNANCY

It is the situation that the pregnancy settles outside the uterine cavity. It is revealed that the ectopic pregnancy risk is less in frozen embryo transfer cycles compared to the fresh embryo cycles. This risk decreases by 5-10 times by preferring frozen embryo transfer.